Both, the handkerchief and the comb can be used by male only. So, being a female player I can't use one of the items to enter the next quest starting at Waupee
10 Stones for solving the quest "Quickly, wake up!". Where can Stones be found?
Looking at The West Calculator, this is the info: http://tw-calc.net/quests/group/199#3127
10 Pebbles it says, got 10 pebbles, but no go on solving that quest...either fix this or have the quest giver give better info/hints in the description of the quest?!
Will be fixed in the next update, the 10 stones will be replaced with 10 Pebbles and you will be able to finish the questline.
The time requirement is a bit weird for this quest, so it might suggest otherwise, but the quest is no longer available unfortunately.